MicroRNA-302b negatively regulates IL-1β production in response to MSU crystals by targeting IRAK4 and EphA2

MicroRNA-302b negatively regulates IL-1β production in response to MSU crystals by targeting IRAK4 and EphA2

Abstract Background Interleukin-1β (IL-1β) is a pivotal proinflammatory cytokine that is strongly associated with the inflammation of gout. However, the underlying mechanism through which the production of IL-1β is regulated has not been fully elucidated. Our previous work identified that miR-302b h...

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Bibliographic Details
Main Authors: Teng Ma, Xiao Liu, Zhifu Cen, Chuan Xin, Mingfeng Guo, Chaoyu Zou, Wenpeng Song, Rou Xie, Kailun Wang, Hong Zhou, Jun Zhang, Zhen Wang, Ce Bian, Kaijun Cui, Jiong Li, Yu-Quan Wei, Jing Li, Xikun Zhou
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Arthritis Research & Therapy
Subjects:
MicroRNA-302b
Interleukin-1β
Gouty arthritis
Online Access:http://link.springer.com/article/10.1186/s13075-018-1528-9

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http://link.springer.com/article/10.1186/s13075-018-1528-9

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