Directed evolution of lipase A from Bacillus subtilis for the preparation of enantiocomplementary sec-alcohols

Biocatalysts with tailor-made or controllable stereoselectivity are valuable and highly desired in the precision synthesis of chiral compounds. Most lipases display excellent (R)-enantioselectivity for various sec-alcohols. In order to reverse the inherent (R)-enantioselectivity of lipase A from Bac...

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Bibliographic Details
Main Authors: Danyang Li, Xiaoyang Chen, Zhichun Chen, Xianfu Lin, Jian Xu, Qi Wu
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2021-08-01
Series:Green Synthesis and Catalysis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666554921000594