Simultaneous selection of nanobodies for accessible epitopes on immune cells in the tumor microenvironment
Abstract In the rapidly advancing field of synthetic biology, there exists a critical need for technology to discover targeting moieties for therapeutic biologics. Here we present INSPIRE-seq, an approach that utilizes a nanobody library and next-generation sequencing to identify nanobodies selected...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-11-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-43038-z |