BAFF- and TACI-Dependent Processing of BAFFR by ADAM Proteases Regulates the Survival of B Cells

BAFF- and TACI-Dependent Processing of BAFFR by ADAM Proteases Regulates the Survival of B Cells

Summary: B cell activating factor (BAFF) provides B cells with essential survival signals. It binds to three receptors: BAFFR, TACI, and BCMA that are differentially expressed by B cell subsets. BAFFR is early expressed in circulating B cells and provides key signals for further maturation. Here, we...

Full description

Bibliographic Details
Main Authors: Cristian R. Smulski, Patrick Kury, Lea M. Seidel, Hannah S. Staiger, Anna K. Edinger, Laure Willen, Maximilan Seidl, Henry Hess, Ulrich Salzer, Antonius G. Rolink, Marta Rizzi, Pascal Schneider, Hermann Eibel
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717301705

Internet

http://www.sciencedirect.com/science/article/pii/S2211124717301705

Similar Items