Screening of major hepatotoxic components of Tripterygium wilfordii based on hepatotoxic injury patterns

Screening of major hepatotoxic components of Tripterygium wilfordii based on hepatotoxic injury patterns

Abstract Background Tripterygium wilfordii Hook. F. (TwHF), a traditional Chinese medicine, is widely used in the treatment of rheumatoid arthritis. Due to multiorgan toxicity, particularly hepatotoxicity, the application of TwHF is restricted. To clarify the hepatotoxic substances, zebrafish, hepat...

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Bibliographic Details
Main Authors: Meng Li, Qiong Luo, Xi Chen, Furong Qiu, Yanyan Tao, Xin Sun, Chenghai Liu
Format: Article
Language:English
Published: BMC 2023-01-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Tripterygium wilfordii hook. F.
Hepatotoxicity
Drug-induced liver injury
Herbal component
Macrophage
Online Access:https://doi.org/10.1186/s12906-023-03836-w

Internet

https://doi.org/10.1186/s12906-023-03836-w

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