The Expression Profiles and Deregulation of UDP-Glycosyltransferase (<i>UGT</i>) Genes in Human Cancers and Their Association with Clinical Outcomes

The Expression Profiles and Deregulation of UDP-Glycosyltransferase (<i>UGT</i>) Genes in Human Cancers and Their Association with Clinical Outcomes

The human UDP-glycosyltransferase (UGTs) superfamily has 22 functional enzymes that play a critical role in the metabolism of small lipophilic compounds, including carcinogens, drugs, steroids, lipids, fatty acids, and bile acids. The expression profiles of <i>UGT</i> genes in human canc...

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Bibliographic Details
Main Authors: Dong Gui Hu, Shashikanth Marri, Peter I. Mackenzie, Julie-Ann Hulin, Ross A. McKinnon, Robyn Meech
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
UDP-glycosyltransferase
UDP-glucuronosyltransferase
cancer
drug metabolism
gene expression
differential gene expression
Online Access:https://www.mdpi.com/2072-6694/13/17/4491

Internet

https://www.mdpi.com/2072-6694/13/17/4491

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