Induction of osteogenesis by bone-targeted Notch activation

Declining bone mass is associated with aging and osteoporosis, a disease characterized by progressive weakening of the skeleton and increased fracture incidence. Growth and lifelong homeostasis of bone rely on interactions between different cell types including vascular cells and mesenchymal stromal...

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Main Authors: Cong Xu, Van Vuong Dinh, Kai Kruse, Hyun-Woo Jeong, Emma C Watson, Susanne Adams, Frank Berkenfeld, Martin Stehling, Seyed Javad Rasouli, Rui Fan, Rui Chen, Ivan Bedzhov, Qi Chen, Katsuhiro Kato, Mara E Pitulescu, Ralf H Adams
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/60183