Preparation of chitosan nanoparticle containing recombinant CD44v antigen and evaluation of its immunization capacity against breast cancer in BALB/c mice
Highlights rCD44v encapsulated by chitosan nanoparticles increases immunological responses. rCD44v increased IgG and IgA titers and some cytokines in the immunized mice. The rCD44v protein has potential features to be used as a vaccine for breast cancer.
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-02-01
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| Series: | BMC Cancer |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12885-023-10614-x |