Methotrexate, an anti-inflammatory drug, inhibits Hepatitis E viral replication
Hepatitis E Virus (HEV) is a positively oriented RNA virus having a 7.2 kb genome. HEV consists of three open reading frames (ORF1-3). Of these, ORF1 codes for the enzymes Methyltransferase (Mtase), Papain-like cysteine protease (PCP), RNA helicase, and RNA-dependent RNA polymerase (RdRp). Unavailab...
Main Authors: | Akash Kumar, Preeti Hooda, Anindita Puri, Radhika Khatter, Mohammed S. Al-Dosari, Neha Sinha, Mohammad K. Parvez, Deepak Sehgal |
---|---|
格式: | Article |
語言: | English |
出版: |
Taylor & Francis Group
2023-12-01
|
叢編: | Journal of Enzyme Inhibition and Medicinal Chemistry |
主題: | |
在線閱讀: | https://www.tandfonline.com/doi/10.1080/14756366.2023.2280500 |
相似書籍
-
Inhibition of Hepatitis E Virus Replication by Novel Inhibitor Targeting Methyltransferase
由: Preeti Hooda, et al.
出版: (2022-08-01) -
The replicative CMG helicase: the ideal target for cancer therapy
由: W. Henderson, et al.
出版: (2020-12-01) -
Identification of 1600 replication origins in S. cerevisiae
由: Eric J Foss, et al.
出版: (2024-02-01) -
Viral replication organelles: the highly complex and programmed replication machinery
由: Hao Deng, et al.
出版: (2024-07-01) -
Oxysterol binding protein (OSBP) contributes to hepatitis E virus replication
由: Shaoli Lin, et al.
出版: (2024-07-01)