Energy stress modulation of AMPK/FoxO3 signaling inhibits mitochondria-associated ferroptosis

Energy stress modulation of AMPK/FoxO3 signaling inhibits mitochondria-associated ferroptosis

Cancer cells and ischemic diseases exhibit unique metabolic responses and adaptations to energy stress. Forkhead box O 3a (FoxO3a) is a transcription factor that plays an important role in cell metabolism, mitochondrial dysfunction and oxidative stress response. Although the AMP-activated protein ki...

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Bibliographic Details
Main Authors: Sufang Zhong, Wenjin Chen, Bocheng Wang, Chao Gao, Xiamin Liu, Yonggui Song, Hui Qi, Hongbing Liu, Tao Wu, Rikang Wang, Baodong Chen
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Redox Biology
Subjects:
AMPK
FoxO3a
Energy stress
Ferroptosis
Lipid peroxidation
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723001611

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http://www.sciencedirect.com/science/article/pii/S2213231723001611

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