Aldehyde dehydrogenase (ALDH) activity does not select for cells with enhanced aggressive properties in malignant melanoma.

BACKGROUND: Malignant melanoma is an exceptionally aggressive, drug-resistant and heterogeneous cancer. Recently it has been shown that melanoma cells with high clonogenic and tumourigenic abilities are common, but markers distinguishing such cells from cells lacking these abilities have not been id...

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Bibliographic Details
Main Authors: Lina Prasmickaite, Birgit Ø Engesaeter, Nirma Skrbo, Tina Hellenes, Alexandr Kristian, Nina K Oliver, Zhenhe Suo, Gunhild M Maelandsmo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2874003?pdf=render