A STAT3 inhibitor ameliorates CNS autoimmunity by restoring Teff:Treg balance
Reestablishing an appropriate balance between T effector cells (Teff) and Tregs is essential for correcting autoimmunity. Multiple sclerosis (MS) is an immune-mediated chronic CNS disease characterized by neuroinflammation, demyelination, and neuronal degeneration, in which the Teff:Treg balance is...
| Главные авторы: | , , , , , , , , , , |
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| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
American Society for Clinical investigation
2021-02-01
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| Серии: | JCI Insight |
| Предметы: | |
| Online-ссылка: | https://doi.org/10.1172/jci.insight.142376 |