Mosaic TP53 Mutation on Tumour Development in Pigs: A Case Study

Pigs rarely develop cancer; however, tumour protein p53 (TP53)-modified pigs may have an increased incidence of cancer. In this study, two pigs with mosaic mutations induced by gene editing were compared to determine the role of the wild-type TP53 sequence in tumorigenesis and to speculate how amino...

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Bibliographic Details
Main Authors: Chommanart Thongkittidilok, Maki Hirata, Qingyi Lin, Nanaka Torigoe, Bin Liu, Yoko Sato, Megumi Nagahara, Fuminori Tanihara, Takeshige Otoi
Format: Article
Language:English
Published: Hindawi Limited 2023-01-01
Series:Veterinary Medicine International
Online Access:http://dx.doi.org/10.1155/2023/7000858