Dendrobium officinale polysaccharide regulated hepatic stellate cells activation and liver fibrosis by inhibiting the SMO/Gli 1 pathway

Dendrobium officinale polysaccharide regulated hepatic stellate cells activation and liver fibrosis by inhibiting the SMO/Gli 1 pathway

Liver fibrosis is a result of chronic liver disease; without treatment, it can progress to cirrhosis and even liver cancer. The occurrence and development of liver fibrosis is closely related to the activation of hepatic stellate cells (HSCs). Many events, including induction of the hedgehog signal...

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Bibliographic Details
Main Authors: Xiawen Yang, Wenting Ji, Zhihong Zhou, Junfeng Wang, Zheng Cui, Xianglin Pan, Huiping Hu, Zihao He, Zhijing Wu, Yu Zhang, Kaiping Wang
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Journal of Functional Foods
Subjects:
Dendrobium officinale polysaccharide
Liver fibrosis
Hepatic stellate cells
Hedgehog signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464623005601

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http://www.sciencedirect.com/science/article/pii/S1756464623005601

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