The function of tcf3 in medaka embryos: efficient knockdown with pePNAs

Abstract Background The application of antisense molecules, such as morpholino oligonucleotides, is an efficient method of gene inactivation in vivo. We recently introduced phosphonic ester modified peptide nucleic acids (PNA) for in vivo loss-of-function experiments in medaka embryos. Here we teste...

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Bibliographic Details
Main Authors: Gerlinde Doenz, Sebastian Dorn, Narges Aghaallaei, Baubak Bajoghli, Elisabeth Riegel, Michaela Aigner, Holger Bock, Birgit Werner, Thomas Lindhorst, Thomas Czerny
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Biotechnology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12896-017-0411-0