Prerequisite Binding Modes Determine the Dynamics of Action of Covalent Agonists of Ion Channel TRPA1

Prerequisite Binding Modes Determine the Dynamics of Action of Covalent Agonists of Ion Channel TRPA1

Transient receptor potential ankyrin 1 (TRPA1) is a transmembrane protein channeling the influx of calcium ions. As a polymodal nocisensor, TRPA1 can be activated by thermal, mechanical stimuli and a wide range of chemically damaging molecules including small volatile environmental toxicants and end...

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Bibliographic Details
Main Authors: Balázs Zoltán Zsidó, Rita Börzsei, Erika Pintér, Csaba Hetényi
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceuticals
Subjects:
TRPA1 receptor
prerequisite binding
covalent binding
Online Access:https://www.mdpi.com/1424-8247/14/10/988

Internet

https://www.mdpi.com/1424-8247/14/10/988

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