Modern and prebiotic amino acids support distinct structural profiles in proteins

The earliest proteins had to rely on amino acids available on early Earth before the biosynthetic pathways for more complex amino acids evolved. In extant proteins, a significant fraction of the ‘late’ amino acids (such as Arg, Lys, His, Cys, Trp and Tyr) belong to essential catalytic and structure-...

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Bibliographic Details
Main Authors: Vyacheslav Tretyachenko, Jiří Vymětal, Tereza Neuwirthová, Jiří Vondrášek, Kosuke Fujishima, Klára Hlouchová
Format: Article
Language:English
Published: The Royal Society 2022-06-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.220040