Modern and prebiotic amino acids support distinct structural profiles in proteins
The earliest proteins had to rely on amino acids available on early Earth before the biosynthetic pathways for more complex amino acids evolved. In extant proteins, a significant fraction of the ‘late’ amino acids (such as Arg, Lys, His, Cys, Trp and Tyr) belong to essential catalytic and structure-...
Main Authors: | Vyacheslav Tretyachenko, Jiří Vymětal, Tereza Neuwirthová, Jiří Vondrášek, Kosuke Fujishima, Klára Hlouchová |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2022-06-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/10.1098/rsob.220040 |
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