Prednisone-hydrogen sulfide releasing hybrid shows improved therapeutic profile in asthma

Prednisone-hydrogen sulfide releasing hybrid shows improved therapeutic profile in asthma

Introduction: Hydrogen sulfide (H2S) is emerging as an important potential therapeutic option for respiratory inflammatory diseases. In this study, we investigated the effectiveness of a novel corticosteroid derivative, that is chemically linked to an H2S donor, in managing asthma features.Methods:...

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Bibliographic Details
Main Authors: Ida Cerqua, Elisabetta Granato, Angela Corvino, Beatrice Severino, Danilo D’Avino, Martina Simonelli, Elisa Perissutti, Antonia Scognamiglio, Davida Mirra, Bruno D’Agostino, Giuseppe Caliendo, Antonietta Rossi, Giuseppe Cirino, Chiara Maria Motta, Fiorentina Roviezzo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Pharmacology
Subjects:
hydrogen sulfide-donor
steroid
airway remodeling
bronchial reactivity
lung inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1266934/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1266934/full

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