Two energy barriers and a transient intermediate state determine the unfolding and folding dynamics of cold shock protein
Force-dependent transitions can provide insights into the free-energy landscape of proteins. Here, the authors observe the folding and unfolding dynamics of the model protein Csp using magnetic tweezers, from which a free-energy landscape with two energy barriers and a transient intermediate state i...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-11-01
|
| Series: | Communications Chemistry |
| Online Access: | https://doi.org/10.1038/s42004-021-00592-1 |