Defining critical illness using immunological endotypes in patients with and without sepsis: a cohort study

Defining critical illness using immunological endotypes in patients with and without sepsis: a cohort study

Abstract Background Sepsis is a heterogenous syndrome with limited therapeutic options. Identifying immunological endotypes through gene expression patterns in septic patients may lead to targeted interventions. We investigated whether patients admitted to a surgical intensive care unit (ICU) with s...

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Bibliographic Details
Main Authors: Jeremy A. Balch, Uan-I Chen, Oliver Liesenfeld, Petr Starostik, Tyler J. Loftus, Philip A. Efron, Scott C. Brakenridge, Timothy E. Sweeney, Lyle L. Moldawer
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Critical Care
Subjects:
Transcriptomics
Biomarkers
ICU
Outcomes
Sepsis
Online Access:https://doi.org/10.1186/s13054-023-04571-x

Internet

https://doi.org/10.1186/s13054-023-04571-x

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