Genetic profiling of the isoprenoid and sterol biosynthesis pathway genes of Trypanosoma cruzi.

In Trypanosoma cruzi the isoprenoid and sterol biosynthesis pathways are validated targets for chemotherapeutic intervention. In this work we present a study of the genetic diversity observed in genes from these pathways. Using a number of bioinformatic strategies, we first identified genes that wer...

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Bibliographic Details
Main Authors: Raúl O Cosentino, Fernán Agüero
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4020770?pdf=render