Tyrosine phosphorylation tunes chemical and thermal sensitivity of TRPV2 ion channel

Tyrosine phosphorylation tunes chemical and thermal sensitivity of TRPV2 ion channel

Transient receptor potential vanilloid 2 (TRPV2) is a multimodal ion channel implicated in diverse physiopathological processes. Its important involvement in immune responses has been suggested such as in the macrophages’ phagocytosis process. However, the endogenous signaling cascades controlling t...

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Bibliographic Details
Main Authors: Xiaoyi Mo, Peiyuan Pang, Yulin Wang, Dexiang Jiang, Mengyu Zhang, Yang Li, Peiyu Wang, Qizhi Geng, Chang Xie, Hai-Ning Du, Bo Zhong, Dongdong Li, Jing Yao
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-06-01
Series:eLife
Subjects:
TRPV2
nociception
temperature gating
phosphorylation
phagocytosis
Online Access:https://elifesciences.org/articles/78301

Internet

https://elifesciences.org/articles/78301

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