Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex

Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex

<p>Abstract</p> <p>Background</p> <p>Disrupting the balance of histone lysine methylation alters the expression of genes involved in tumorigenesis including proto-oncogenes and cell cycle regulators. Methylation of lysine residues is commonly catalyzed by a family of pr...

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Bibliographic Details
Main Authors: Gottlieb Paul D, Sims Robert J, Brown Mark A, Tucker Philip W
Format: Article
Language:English
Published: BMC 2006-06-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/5/1/26

Internet

http://www.molecular-cancer.com/content/5/1/26

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