A metagenomics method for the quantitative detection of bacterial pathogens causing hospital-associated and ventilator-associated pneumonia

A metagenomics method for the quantitative detection of bacterial pathogens causing hospital-associated and ventilator-associated pneumonia

ABSTRACT The management of ventilator-associated and hospital-acquired pneumonia requires rapid and accurate quantitative detection of the infecting pathogen(s). To achieve this, we propose a metagenomics next-generation sequencing (mNGS) assay that includes the use of an internal sample processing...

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Bibliographic Details
Main Authors: S. Hauser, V. Lazarevic, M. Tournoud, E. Ruppé, E. Santiago Allexant, G. Guigon, S. Schicklin, V. Lanet, M. Girard, C. Mirande, G. Gervasi, J. Schrenzel
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
clinical metagenomics
diagnosis
standardization
sample processing control
spike-in bacteria
calibrator
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01294-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.01294-23

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