Evidence for mitochondrial respiratory deficiency in rat rhabdomyosarcoma cells.

BACKGROUND: Mitochondria can sense signals linked to variations in energy demand to regulate nuclear gene expression. This retrograde signaling pathway is presumed to be involved in the regulation of myoblast proliferation and differentiation. Rhabdomyosarcoma cells are characterized by their failur...

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Bibliographic Details
Main Authors: Vanessa E Jahnke, Odile Sabido, Aurélia Defour, Josiane Castells, Etienne Lefai, Damien Roussel, Damien Freyssenet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2797644?pdf=render