Sprouty4 correlates with favorable prognosis in perihilar cholangiocarcinoma by blocking the FGFR-ERK signaling pathway and arresting the cell cycle

Background: Perihilar cholangiocarcinoma (PHCC) is the most common subtype of cholangiocarcinoma(CCA). We previously investigated the expression pattern of Sprouty(SPRY) in intrahepatic cholangiocarcinoma(ICC), but the expression and clinical significance of SPRY family members in PHCC are still unk...

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Bibliographic Details
Main Authors: Bo Qiu, Tianli Chen, Rongqi Sun, Zengli Liu, Xiaoming Zhang, Zhipeng Li, Yunfei Xu, Zongli Zhang
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419307704