Knockdown of Ift88 in fibroblasts causes extracellular matrix remodeling and decreases conduction velocity in cardiomyocyte monolayers
Background: Atrial fibrosis plays an important role in the development and persistence of atrial fibrillation by promoting reentry. Primary cilia have been identified as a regulator of fibroblasts (FB) activation and extracellular matrix (ECM) deposition. We hypothesized that selective reduction of...
| Автори: | , , , , , , , |
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| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Frontiers Media S.A.
2022-11-01
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| Серія: | Frontiers in Physiology |
| Предмети: | |
| Онлайн доступ: | https://www.frontiersin.org/articles/10.3389/fphys.2022.1057200/full |