The Effect of Overexpressed DdRabS on Development, Cell Death, Vesicular Trafficking, and the Secretion of Lysosomal Glycosidase Enzymes

The Effect of Overexpressed DdRabS on Development, Cell Death, Vesicular Trafficking, and the Secretion of Lysosomal Glycosidase Enzymes

Rab GTPases are essential regulators of many cellular processes and play an important role in downstream signaling vital to proper cell function. We sought to elucidate the role of novel D. discoideum GTPase RabS. Cell lines over-expressing DdRabS and expressing DdRabS N137I (dominant negative (DN))...

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Bibliographic Details
Main Authors: Azure Yarbrough, Katherine Maringer, Entsar J. Saheb, Sanaa Jawed, John Bush
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Biology
Subjects:
Dictyostelium
RabS
vesicular trafficking
lysosomal enzymes
β-glucosidase
GTPase
development
cell death
Online Access:http://www.mdpi.com/2079-7737/7/2/33

Internet

http://www.mdpi.com/2079-7737/7/2/33

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