Probing Functional Changes in Exocyst Configuration with Monoclonal Antibodies

Spatial regulation of exocytosis relies on the exocyst, a hetero-octameric protein complex that tethers vesicles to fusion sites at the plasma membrane. Nevertheless, our understanding of mechanisms regulating exocyst assembly/disassembly, localization and function are incomplete. Here, we have ex...

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Bibliographic Details
Main Authors: Shivangi M. Inamdar, Shu-Chan eHsu, Charles eYeaman
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2016.00051/full