Adding Concurrent Chemotherapy to Intensity-Modulated Radiotherapy Does Not Improve Treatment Outcomes for Stage II Nasopharyngeal Carcinoma: A Phase 2 Multicenter Clinical Trial

Purpose: To explore the efficacy of concomitant chemotherapy in intensity-modulated radiotherapy (IMRT) to treat stage II nasopharyngeal carcinoma (NPC).Methods and Materials: In this randomized phase 2 study [registered with ClinicalTrials.gov (NCT01187238)], eligible patients with stage II (2010 U...

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Main Authors: Xiaodong Huang, Xiaozhong Chen, Chong Zhao, Jingbo Wang, Kai Wang, Lin Wang, Jingjing Miao, Caineng Cao, Ting Jin, Ye Zhang, Yuan Qu, Xuesong Chen, Qingfeng Liu, Shiping Zhang, Jianghu Zhang, Jingwei Luo, Jianping Xiao, Guozhen Xu, Li Gao, Junlin Yi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01314/full