Biosynthesis of L‐5‐methyltetrahydrofolate by genetically engineered Escherichia coli

Abstract L‐5‐Methyltetrahydrofolate (L‐5‐MTHF) is the only biologically active form of folate in the human body. Production of L‐5‐MTHF by using microbes is an emerging consideration for green synthesis. However, microbes naturally produce only a small amount of L‐5‐MTHF. Here, Escherichia coli BL21...

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Bibliographic Details
Main Authors: Yubo Wang, Meng Zhang, Lexin Li, Jihong Yi, Jiyu Liang, Shuning Wang, Ping Xu
Format: Article
Language:English
Published: Wiley 2022-11-01
Series:Microbial Biotechnology
Online Access:https://doi.org/10.1111/1751-7915.14139