A mitochondrial checkpoint to adaptive anticancer immunity

BCL2 robustly preserves mitochondrial integrity, hence inhibiting innate immune signaling and apoptotic cell death in several cell types. Here, we comment on our recent data demonstrating that BCL2 also limits the ability of dendritic cells to elicit adaptive immune responses, lending support to a u...

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Bibliographic Details
Main Authors: Oliver Kepp, Peng Liu, Guido Kroemer, Lorenzo Galluzzi
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:OncoImmunology
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2023.2271693