Effect of obesity on early blood–brain barrier disruption following transient focal cerebral ischemia

Summary Objective We determined the effect of obesity on early post‐ischemic blood–brain barrier (BBB) disruption. Methods Male C57BL/6J mice were fed a high‐fat diet (HFD) or standard chow for 16 weeks. Transient focal cerebral ischemia was induced by directly ligating the middle cerebral artery fo...

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Bibliographic Details
Main Authors: C. Li, Z. Jiang, W. Lu, D. Arrick, K. McCarter, H. Sun
Format: Article
Language:English
Published: Wiley 2016-03-01
Series:Obesity Science & Practice
Subjects:
Online Access:https://doi.org/10.1002/osp4.30