Role of Trypanosoma cruzi trans-sialidase on the escape of host immune surveillance

Chagas disease is caused by the flagellate protozoan Trypanosoma cruzi, affecting millions of people throughout Latin America. The parasite dampens host immune response causing modifications in diverse lymphoid compartments, including the thymus. T. cruzi trans-sialidase (TS) seems to play a fundame...

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Bibliographic Details
Main Authors: Ana Flávia Fernandes Ribas Nardy, Celio Geraldo Freire De Lima, Ana Rosa ePérez, Alexandre eMorrot
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00348/full