Structure and Dynamics Guiding Design of Antibody Therapeutics and Vaccines

Structure and Dynamics Guiding Design of Antibody Therapeutics and Vaccines

Antibodies and other new antibody-like formats have emerged as one of the most rapidly growing classes of biotherapeutic proteins. Understanding the structural features that drive antibody function and, consequently, their molecular recognition is critical for engineering antibodies. Here, we presen...

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Bibliographic Details
Main Authors: Monica L. Fernández-Quintero, Nancy D. Pomarici, Anna-Lena M. Fischer, Valentin J. Hoerschinger, Katharina B. Kroell, Jakob R. Riccabona, Anna S. Kamenik, Johannes R. Loeffler, James A. Ferguson, Hailee R. Perrett, Klaus R. Liedl, Julianna Han, Andrew B. Ward
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Antibodies
Subjects:
antibody
structure prediction
antibody structure determination
molecular dynamics
X-ray crystallography
NMR
Online Access:https://www.mdpi.com/2073-4468/12/4/67

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https://www.mdpi.com/2073-4468/12/4/67

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