Three-dimensional human bile duct formation from chemically induced human liver progenitor cells

Three-dimensional human bile duct formation from chemically induced human liver progenitor cells

Background: The intrahepatic bile ducts (BDs) play an important role in the modification and transport of bile, and the integration between the BD and hepatocytes is the basis of the liver function. However, the lack of a source of cholangiocytes limits in vitro research. The aim of the present stud...

Full description

Bibliographic Details
Main Authors: Peilin Li, Daisuke Miyamoto, Yu Huang, Tomohiko Adachi, Masaaki Hidaka, Takanobu Hara, Akihiko Soyama, Hajime Matsushima, Hajime Imamura, Kengo Kanetaka, Weili Gu, Susumu Eguchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
chemically induced progenitor cell
cholangiocyte
bile duct regeneration
bile canaliculi
hepatic organoid
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1249769/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1249769/full

Similar Items