Expression of Fibroblast Activation Protein Is Enriched in Neuroendocrine Prostate Cancer and Predicts Worse Survival

Expression of Fibroblast Activation Protein Is Enriched in Neuroendocrine Prostate Cancer and Predicts Worse Survival

Background: Advanced prostate cancer (PC) may accumulate genomic alterations that hallmark lineage plasticity and transdifferentiation to a neuroendocrine (NE) phenotype. Fibroblast activation protein (FAP) is a key player in epithelial-to-mesenchymal transition (EMT). However, its clinical value an...

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Bibliographic Details
Main Authors: Panagiotis J. Vlachostergios, Athanasios Karathanasis, Vassilios Tzortzis
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Genes
Subjects:
fibroblast activating protein
neuroendocrine differentiation
prostate cancer
castration-resistant
androgen receptor
Online Access:https://www.mdpi.com/2073-4425/13/1/135

Internet

https://www.mdpi.com/2073-4425/13/1/135

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