<i>DOCK2</i> Mutation and Recurrent Hemophagocytic Lymphohistiocytosis

<i>DOCK2</i> Mutation and Recurrent Hemophagocytic Lymphohistiocytosis

Hemophagocytic lymphohistiocytosis (HLH) is a syndrome resulting from uncontrolled hyper-inflammation, excessive immune system activation, and elevated levels of inflammatory cytokines. HLH can be caused by the inability to downregulate activated macrophages by natural killer (NK) and CD8 cytotoxic...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän: Daniel D. Reiff, Mingce Zhang, Randy Q. Cron
Materialtyp: Artikel
Språk:English
Publicerad: MDPI AG 2023-02-01
Serie:Life
Ämnen:
hemophagocytic lymphohistiocytosis
inflammation
natural killer cell
macrophage
cytolysis
degranulation
Länkar:https://www.mdpi.com/2075-1729/13/2/434

Internet

https://www.mdpi.com/2075-1729/13/2/434

Liknande verk