Using a synthetic machinery to improve carbon yield with acetylphosphate as the core

Abstract In microbial cell factory, CO2 release during acetyl-CoA production from pyruvate significantly decreases the carbon atom economy. Here, we construct and optimize a synthetic carbon conserving pathway named as Sedoheptulose-1,7-bisphosphatase Cycle with Trifunctional PhosphoKetolase (SCTPK)...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Likun Guo, Min Liu, Yujia Bi, Qingsheng Qi, Mo Xian, Guang Zhao
التنسيق: مقال
اللغة:English
منشور في: Nature Portfolio 2023-08-01
سلاسل:Nature Communications
الوصول للمادة أونلاين:https://doi.org/10.1038/s41467-023-41135-7