Physical exercise promotes astrocyte coverage of microvessels in a model of chronic cerebral hypoperfusion

Abstract Background Brain circulation disorders such as chronic cerebral hypoperfusion have been associated with a decline in cognitive function during the development of dementia. Astrocytes together with microglia participate in the immune response in the CNS and make them potential sentinels in t...

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Main Authors: Marina Leardini-Tristão, Giulia Andrade, Celina Garcia, Patrícia A. Reis, Millena Lourenço, Emilio T. S. Moreira, Flavia R. S. Lima, Hugo C. Castro-Faria-Neto, Eduardo Tibirica, Vanessa Estato
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12974-020-01771-y