Peroxynitrite is a key mediator of the cardioprotection afforded by ischemic postconditioning in vivo.

Myocardial ischemic postconditioning (PosC) describes an acquired resistance to lethal ischemia-reperfusion (I/R) injury afforded by brief episodes of I/R applied immediately after the ischemic insult. Cardioprotection is conveyed by parallel signaling pathways converging to prevent mitochondria per...

Full description

Bibliographic Details
Main Authors: Jianhui Li, Noureddine Loukili, Nathalie Rosenblatt-Velin, Pal Pacher, François Feihl, Bernard Waeber, Lucas Liaudet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3707883?pdf=render