Reconsidering the role of blood-brain barrier in Alzheimer’s disease: From delivery to target

Reconsidering the role of blood-brain barrier in Alzheimer’s disease: From delivery to target

The existence of a selective blood-brain barrier (BBB) and neurovascular coupling are two unique central nervous system vasculature features that result in an intimate relationship between neurons, glia, and blood vessels. This leads to a significant pathophysiological overlap between neurodegenerat...

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Bibliographic Details
Main Authors: João André Sousa, Catarina Bernardes, Sara Bernardo-Castro, Miguel Lino, Inês Albino, Lino Ferreira, José Brás, Rita Guerreiro, Miguel Tábuas-Pereira, Inês Baldeiras, Isabel Santana, João Sargento-Freitas
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
blood-brain barrier
nanomaterials
Alzheimer’s disease
neurodegenerative diseases
amyloid clearance
genetic targeting
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1102809/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2023.1102809/full

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