Murine neural stem/progenitor cells protect neurons against ischemia by HIF-1alpha-regulated VEGF signaling.

Focal cerebral ischemia following middle cerebral artery occlusion (MCAO) stimulates a robust cytogenic response from the adult subventricular zone (SVZ) that includes massive proliferation of neural stem/progenitor cells (NSPCs) and cellular migration into the injury area. To begin to explore benef...

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Bibliographic Details
Main Authors: Kate M Harms, Lu Li, Lee Anna Cunningham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2842303?pdf=render