Listeria exploits IFITM3 to suppress antibacterial activity in phagocytes

Listeria exploits IFITM3 to suppress antibacterial activity in phagocytes

Interferon (IFN) is an important component of antiviral immunity, but can also be exploited by bacteria for immune evasion. Here the authors show that Listeria monocytogenes (Lm) induces type I IFN to suppress the degradation of Lm virulence proteins, ActA and LLO, and promote Lm infection in an IFI...

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Bibliographic Details
Main Authors: Joel M. J. Tan, Monica E. Garner, James M. Regeimbal, Catherine J. Greene, Jorge D. Rojas Márquez, Dustin A. Ammendolia, Adam R. R. McCluggage, Taoyingnan Li, Katherine J. Wu, Marija Cemma, Philip P. Ostrowski, Brian Raught, Michael S. Diamond, Sergio Grinstein, Robin M. Yates, Darren E. Higgins, John H. Brumell
Format: Article
Language:English
Published: Nature Portfolio 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24982-0

Internet

https://doi.org/10.1038/s41467-021-24982-0

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