Characterization of Asparagine Deamidation in Immunodominant Myelin Oligodendrocyte Glycoprotein Peptide Potential Immunotherapy for the Treatment of Multiple Sclerosis

Characterization of Asparagine Deamidation in Immunodominant Myelin Oligodendrocyte Glycoprotein Peptide Potential Immunotherapy for the Treatment of Multiple Sclerosis

Mannan (polysaccharide) conjugated with a myelin oligodendrocyte glycoprotein (MOG) peptide, namely (KG)<sub>5</sub>MOG<sub>35–55</sub>, represents a potent and promising new approach for the immunotherapy of Multiple Sclerosis (MS). The MOG<sub>35–55</sub> epitop...

Full description

Bibliographic Details
Main Authors: Maria-Eleni Androutsou, Agathi Nteli, Areti Gkika, Maria Avloniti, Anastasia Dagkonaki, Lesley Probert, Theodore Tselios, Simona Golič Grdadolnik
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
asparagine deamidation
nuclear magnetic resonance
myelin oligodentrocyte glycoprotein
experimental autoimmune encephalomyelitis
multiple sclerosis
Online Access:https://www.mdpi.com/1422-0067/21/20/7566

Internet

https://www.mdpi.com/1422-0067/21/20/7566

Similar Items