Genetic dissection of acute ethanol responsive gene networks in prefrontal cortex: functional and mechanistic implications.

Individual differences in initial sensitivity to ethanol are strongly related to the heritable risk of alcoholism in humans. To elucidate key molecular networks that modulate ethanol sensitivity we performed the first systems genetics analysis of ethanol-responsive gene expression in brain regions o...

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Bibliographic Details
Main Authors: Aaron R Wolen, Charles A Phillips, Michael A Langston, Alex H Putman, Paul J Vorster, Nathan A Bruce, Timothy P York, Robert W Williams, Michael F Miles
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3325236?pdf=render