Dexpanthenol protects against lipopolysaccharide-induced acute kidney injury by restoring aquaporin-2 levels via regulation of the silent information regulator 1 signaling pathway

Dexpanthenol protects against lipopolysaccharide-induced acute kidney injury by restoring aquaporin-2 levels via regulation of the silent information regulator 1 signaling pathway

Background Acute kidney injury (AKI) is a serious pathology that causes dysfunction in concentrating urine due to kidney damage, resulting in blood pressure dysregulation and increased levels of toxic metabolites. Dexpanthenol (DEX), a pantothenic acid analog, exhibits anti-inflammatory and anti-apo...

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Bibliographic Details
Main Authors: Eyyüp Sabri Özden, Halil Aşcı, Halil İbrahim Büyükbayram, Mehmet Abdulkadir Sevük, Orhan Berk İmeci, Hatice Kübra Doğan, Özlem Özmen
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2023-10-01
Series:Korean Journal of Anesthesiology
Subjects:
apoptosis
caspase 3
dexpanthenol
kidney
oxidative stress
sirtuin 1
Online Access:http://ekja.org/upload/pdf/kja-23207.pdf

Internet

http://ekja.org/upload/pdf/kja-23207.pdf

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