Single cell RNA sequencing unravels mechanisms underlying senescence-like phenotypes of alveolar macrophages

Single cell RNA sequencing unravels mechanisms underlying senescence-like phenotypes of alveolar macrophages

Summary: Alveolar macrophages (AMs) are resident innate immune cells that play vital roles in maintaining lung physiological functions. However, the effects of aging on their dynamics, heterogeneity, and transcriptional profiles remain to be fully elucidated. Through single cell RNA sequencing (scRN...

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Bibliographic Details
Main Authors: Yue Wu, Shengen Shawn Hu, Ruixuan Zhang, Nick P. Goplen, Xiaochen Gao, Harish Narasimhan, Ao Shi, Yin Chen, Ying Li, Chongzhi Zang, Haidong Dong, Thomas J. Braciale, Bibo Zhu, Jie Sun
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Bioinformatics
Omics
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223012749

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http://www.sciencedirect.com/science/article/pii/S2589004223012749

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