Single cell RNA sequencing unravels mechanisms underlying senescence-like phenotypes of alveolar macrophages

Summary: Alveolar macrophages (AMs) are resident innate immune cells that play vital roles in maintaining lung physiological functions. However, the effects of aging on their dynamics, heterogeneity, and transcriptional profiles remain to be fully elucidated. Through single cell RNA sequencing (scRN...

ver descrição completa

Detalhes bibliográficos
Principais autores: Yue Wu, Shengen Shawn Hu, Ruixuan Zhang, Nick P. Goplen, Xiaochen Gao, Harish Narasimhan, Ao Shi, Yin Chen, Ying Li, Chongzhi Zang, Haidong Dong, Thomas J. Braciale, Bibo Zhu, Jie Sun
Formato: Artigo
Idioma:English
Publicado em: Elsevier 2023-07-01
coleção:iScience
Assuntos:
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2589004223012749